Catalog Number - 68040-SP-PG1-3

Cogent NP Amino Wide Pore Semi Prep Guard Column Cartridges are packed with the same propyl amino bonded stationary phase used in Cogent NP Amino Wide Pore semi-preparative columns. Manufactured on high-purity 300 Å wide pore silica, these guard cartridges protect the semi-preparative column from particulates, strongly retained contaminants, and sample matrix components that can reduce chromatographic performance and shorten column life. The amino chemistry is suitable for both Normal Phase and HILIC applications while providing USP L8 selectivity.

68040-SP-PG1-3 is a semi-preparative guard column cartridge packed with 10 µm NP Amino Wide Pore particles featuring a 300 Å pore size in a 10 mm ID x 10 mm format. Installed ahead of the semi-preparative column, it captures contaminants before they reach the packed bed, helping maintain chromatographic efficiency, improve reproducibility, and extend column lifetime in demanding purification applications. The wide pore structure improves accessibility for larger molecules including complex carbohydrates and other high molecular weight polar compounds.

These guard cartridges are specifically designed for use with 10 mm ID Cogent NP Amino Wide Pore Semi Prep Columns and are housed in durable stainless-steel hardware with stainless-steel frits for reliable operation under semi-preparative flow conditions.

Key Benefits

• NP Amino Wide Pore stationary phase

• USP L8 equivalent chemistry

• Propyl amino bonded phase

• 300 Å wide pore silica

• Suitable for Normal Phase chromatography

• Suitable for HILIC applications

• Protects semi-preparative columns from particulates and contaminants

• Improves access for larger molecules

• Helps maintain column efficiency and reproducibility

• Extends semi-preparative column lifetime

Typical Applications

• Semi-preparative chromatography

• USP L8 methods

• HILIC separations

• Normal Phase chromatography

• Complex sugar purification

• Carbohydrate purification

• Organic acid purification

• Pharmaceutical purification

• Sample cleanup prior to purification

• Semi-preparative column protection

Specifications

• Product Type: Semi Prep Guard Column Cartridges

• Stationary Phase: NP Amino Wide Pore

• USP Classification: L8

• Chromatography Mode: Normal Phase / HILIC

• Bonded Phase: Propyl Amino

• Endcapping: Not Endcapped

• Particle Size: 10 µm

• Pore Size: 300 Å

• Cartridge Dimensions: 10 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 5/PK

• Brand: Cogent

Guard Column Holder Requirement

• A Cogent 10 mm ID Prep Guard Column Holder is required for use with these guard column cartridges.

• View the Cogent 10 mm ID Prep Guard Column Holder (83000-SP-GH)

Special Order Item Information

• Contact Customer Service for quotation, lead time, and ordering assistance.

• Learn more about Special Order Items and ordering policies.

Important Notes

• Packed and shipped in Normal Phase solvents

• Suitable for both Normal Phase and HILIC chromatographic modes

• Wide pore design improves access for larger molecules and complex carbohydrates

• Designed for use with 10 mm ID NP Amino Wide Pore Semi Prep Columns

• Helps protect semi-preparative columns from contamination and premature fouling

• A Cogent 10 mm ID Prep Guard Column Holder (83000-SP-GH) is required

• Requires an HPLC system capable of supporting semi-preparative flow rates

• This is a Special Order Item

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